NO! I CAN do that.

FemaleWhiteLab-AAES001042Today’s blog is written by guest blogger Jessica Laux, a production scientist at Promega Corporation. Jessica spends most of her time in clean rooms. She graduated from the University of Wisconsin-Madison with a B.S. in Natural Science-Animal Sciences.

I was always a very stubborn, defiant child. This is evidenced by the fact that my very first word was “NO!”, which I screamed at the top of my lungs after I had been scolded for pulling all the pots and pans out of the kitchen cupboards. Years later, I still scream “NO!” at times, though I’ve refrained from making a mess of the kitchen lately. That same defiant spirit contributed a great deal to my chosen career.

At a ripe age of ten, I determined I was destined to become a great doctor. My preparation for this career involved writing morbid stories where I brought the dead back to life, as well as poring over the pages of a medical diagnostic book I had claimed as mine. I was not deterred by my inability to understand the big words. I was still able to draw the detailed human anatomy and skeletons with an impressive precision. A couple years later, an adult whom I trusted told me that science and medicine were fields for men only. This same person encouraged me to pursue my artistic talents instead. Continue reading “NO! I CAN do that.”

Career Development for Working Professionals: UW Master of Science in Biotechnology Program

Prior to the Masters in Biotechnology program, I had no working knowledge of Intellectual Property (IP), e.g., patents, trademarks, etc. The M.S. in Biotechnology program not only opened my eyes to Intellectual Property and its importance in biotechnology companies, but it sparked my interested in a career in an IP field. From the knowledge I gained and connections made in the program, I have been able to achieve a career in IP. I am now happy to be able to share my experience and knowledge with current and future students in the program.
—Heather Gerard, M.S. (2006) Intellectual Property Manager, Promega Corporation

Since 2002, the BioPharmaceutical Technology Center Institute (BTC Institute) has been effectively collaborating with the UW Master of Science in Biotechnology Program (MS-Biotechnology) to provide the three lab-based Molecular Technologies courses for this unique degree designed for working professionals.

As noted on the program’s web site, it offers:

  • A curriculum like no other that integrates topics in science, business and law
  • Powerful skills that bring the “big picture” of life science product development into clear focus
  • Exclusive evening/weekend courses allowing you to work full-time while enrolled, and
  • A completed degree in less than two years

Continue reading “Career Development for Working Professionals: UW Master of Science in Biotechnology Program”

Biotechnology Youth Apprenticeship Program Fosters Young Scientists

Student working in laboratory.
Photo credit: BTC Institute.
Ellyn Lepinski is an intern at Promega who started her biotechnology career path five years ago as a high school junior taking a course from the BTC Institute (www.btci.org) as part of the Biotechnology Youth Apprenticeship Program.

Ellyn credits the program with helping her achieve her goals:

“Over the course of two years in which I was a Youth Apprentice, I obtained numerous skills, both inside and outside of the lab. I gained valuable scientific experience, including techniques like gel electrophoresis, nucleic acid purification, PCR, SDS-PAGE, Western blotting, cell culture and more.

On a personal level, I became very close with other students in the class and with our instructors, Barbara Bielec and Chad Zimprich. Everyone involved was always very approachable and willing to help with both laboratory tasks and in terms of giving advice for the future.

Through the program, I was placed in Dr. Que Lan’s entomology lab at UW-Madison, beginning in 2009. While there, I worked on a project involving sterol carrier protein-2, a protein involved in cholesterol uptake in mosquitoes.Notably, I am still working in Dr. Lan’s lab, however my research focus has shifted to bacterial fermentation. In between working in Dr. Lan’s lab, I also worked at the Forest Products Laboratory (USDA).

Additionally, this past June, I began an internship at Promega in the Scientific Applications department. Here I work to develop new applications for existing projects. This November marks five years of laboratory research for me, which would not have been possible without the Youth Apprenticeship Program and everyone involved. In addition to the specific labs that I have had the opportunity to work in, my experience in the Youth Apprenticeship Program has allowed me to emerge as a leader in my college lab courses. The program has clearly made a phenomenal impact on my life and is something I am very grateful for.”

Photo credit: BTC Institute.
Photo credit: BTC Institute.
Since 1993, the BTC Institute in partnership with the Dane County School Consortium has helped make such opportunities possible to nearly 300 students from public schools throughout Dane County. The program includes a paid apprenticeship in an industry or UW-Madison research lab and specialized instruction. In addition to being paid for their work, students receive high school credit for their participation in the worksite and the specialized biotechnology course held at the BTC Institute.

One aspect of the program that makes it so effective and unique is the amount of time that students spend working. Youth apprentices who start as juniors in the program must work 900 paid work hours to earn the Science, Technology, Engineering and Math (STEM) Skill Standards Certificate from the State of Wisconsin, youth apprentices who start work as seniors must earn 450 work hours. Students have had employment at a variety of companies and UW-Madison research labs, a few examples that have hired multiple apprentices include Genus PIC (ABS), MOFA Global, Promega and laboratories in the UW-Madison Departments of Bacteriology, Biochemistry, Entomology, Genetics, Horticulture, Plant Pathology and Surgery. Many of the students, like Ellyn, continue to be employed by their worksite long after they graduate from high school—proof of how effective this program is in helping to create the next generation STEM workforce.

Each year the BTC Institute hosts a Youth Apprenticeship Program preview night for all of the Dane County youth apprenticeship options: biotechnology, automotive technician, health services, and many more (www.dcsc.org). This year the preview nights will be held February 24 and 25 starting at 5:00pm. Students in grades 10 and 11 who are interested in learning more about the program are encouraged to attend one of the evening sessions with a parent.

Fold It Up and Discover a Whole New World

FIGURE 1: Foldscope design, components and usage. (A) CAD layout of Foldscope paper components on an A4 sheet. (B) Schematic of an assembled Foldscope illustrating panning, and (C) cross-sectional view illustrating flexure-based focusing. (D) Foldscope components and tools used in the assembly, including Foldscope paper components, ball lens, button-cell battery, surface-mounted LED, switch, copper tape and polymeric filters. (E) Different modalities assembled from colored paper stock. (F) Novice users demonstrating the technique for using the Foldscope. (G) Demonstration of the field-rugged design, such as stomping under foot.
FIGURE 1: Foldscope design, components and usage.
(A) CAD layout of Foldscope paper components on an A4 sheet. (B) Schematic of an assembled Foldscope illustrating panning, and (C) cross-sectional view illustrating flexure-based focusing. (D) Foldscope components and tools used in the assembly, including Foldscope paper components, ball lens, button-cell battery, surface-mounted LED, switch, copper tape and polymeric filters. (E) Different modalities assembled from colored paper stock. (F) Novice users demonstrating the technique for using the Foldscope. (G) Demonstration of the field-rugged design, such as stomping under foot.

Scientific inquiry —looking at the world and asking questions about what we observe—is a natural human behavior. Why is the sky blue? What would happen if I did this Mom? Ask any grade school teacher. Kids do science naturally. They are not afraid of questions. They are not afraid of nature. They are not afraid of experiments and data collection.

One other things kids do really well is: fold paper. I never cease to be amazed at the elaborate fortune tellers, hoppers, boats, hats and other creations that my daughter and her friends make at a moment’s notice out of virtually any scrap of paper they can find.

Recently members of the Prakash Lab at Standford University announced the Foldscope: an optical microscope that is printed and folded from a single flat sheet of paper. These microscopes, which can provide magnification of up to 2000X, can be produced for less than $1.00/each. Furthermore these scopes weigh less than 10g (a couple of coins), require no external power source, can be dropped from 3-stories without damage, and can even be stepped on.

These characteristics make the Foldscope ideal for field work, particularly in remote locations where access to power and other resources is difficult. Prakash and colleagues have published their work in a PLOS One paper and have demonstrated many uses for these Foldscopes including high-resolution brightfield microscopy, fluorescence microscopy, and darkfield microscopy. Continue reading “Fold It Up and Discover a Whole New World”

Fun Friday Science Videos

For your Friday entertainment, I am posting a couple of videos from my favorite chemists. These examples show slow motion views of some well-known chemical reactions.

The Iodine Clock

[youtube http://www.youtube.com/watch?v=KWJpKNQfXWo?feature=player_embedded&w=640&h=360]

Copper Sulfate in Slow Motion
[youtube http://www.youtube.com/watch?v=jxoHB_sTkI8?feature=player_embedded&w=640&h=360]

See more of these at the Periodic Table of Videos

Paying it Forward: A Promega Employee’s Experience With the American Chemical Society

bharatACSIf you are a scientist you know the American Chemical Society (ACS) for their high quality journals (all 39 of them) and for their annual meetings and conferences. But did you know the ACS also focuses on community education and outreach? The ACS mission is “Improving people’s lives through the transforming power of chemistry.” According to their website, ACS has 189 local chapters at colleges and universities around the country. Bharat Mankani (in the white coat in the photo) tells us about his work with the ACS chapter at Texas A&M.

1. How long have you worked here at Promega and what do you do? Continue reading “Paying it Forward: A Promega Employee’s Experience With the American Chemical Society”

Getting Our Hands Into Some Good Ol’ Home Science

static_detection-simple_electroscopeFor many, this time of year brings with it the opportunity to enjoy a bit of holiday fun with kids. In fact just recently I had the chance to spend a day doing several home science activities with my four- and seven-year old boys. All were simple to set up using commonly found household items in a way that was both instructive and rewarding. Continue reading “Getting Our Hands Into Some Good Ol’ Home Science”