Reporter assays using a single reporter, be it from a stable cell line or transient transfection, can benefit from normalization. Obviously, we are not talking about adding a second control reporter but normalizing to the number of live or dead cells in the well.  Two cell health assays, CellTiter-Fluor™ Cell Viability Assay and CellTox™ Green Cytotoxicity Assay, are ideally suited for multiplexing with reporter assays. 

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