suPAR: A New Approach to Treating Cardiovascular Disease

Cardiovascular disease (CVD), continues to be the leading cause of death in the United States and worldwide. Many patients with CVD have signs of chronic kidney disease (CKD), and those with CKD are often times disproportionately affected by CVD.

This interconnectedness was further explored in a recent study published in the Journal of Clinical Investigation that identified a new immune target, suPAR, as a protein that causes kidney disease and atherosclerosis, the most common form of CVD. Unlike traditional approaches to treating CVD such as controlling blood pressure and lowering cholesterol, this breakthrough research offers a new approach to treatment from an entirely different perspective.

Continue reading “suPAR: A New Approach to Treating Cardiovascular Disease”

“Baby, you have the dreamiest antibodies…”

There’s likely a percentage of the readers of this blog who, if presented with a photo montage of George Clooney, Brad Pitt, Javier Bardem, Daniel Craig, Denzel Washington, Ryan Gosling and other celebrity heartthrobs, might have to take a moment (or several) just to sit back, breathe deeply and appreciate the view. And who could blame us? They’re manly men, all. Easy on the eyes, fairly dripping with testosterone, make our hearts go pitter-pat, maybe make our loins jump just a little with subconscious fantasies of beautiful Clooney babies. What? It’s only natural! It’s biology!

But a recent research effort, published in the February 21 edition of the journal Nature Communications, asserts that our twitterpation (or Brad Pitterpation, as it were) may not be so much for these guys’ handsome faces, strong jawlines, broad shoulders, six-pack abs, that spot in the crook of their neck that probably smells really good…

*sigh*
*batting eyelashes*

Sorry, got distracted there for a second. No, it might not be their looks that we’re really lusting after, but their…robust immune systems? Their drop-dead sexy antibodies? Continue reading ““Baby, you have the dreamiest antibodies…””