There are new developments in genetics coming to light every day, each with the potential to dramatically change life as we know it. The increasingly controversial gene editing system, dubbed CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), is at the root of it all. Harnessed for use in genome editing in 20131, CRISPR has given […]
Recently a FaceBook friend of mine (who is not a scientist) shared a video from WIRED Science where the concept of CRISPR is explained at 5 Levels of Difficulty— for a 7 year old, a teenager, a college student, a grad student and a CRISPR expert. First it was pretty amazing to me that my […]
CRISPR is a hot topic right now, and rightly so—it is revolutionizing research that relies on editing genes. But what exactly is CRISPR? How does it work? Why is everyone so interested in using it? Today’s blog is a beginner’s guide on how CRISPR works with an overview of some new applications of this technology […]
Approximately 30 million years ago, a retrovirus integrated into the germline of a common ancestor of baboons, gorillas, chimpanzees and humans. That endogenous retrovirus, now known as gammaretrovirus human endogenous retrovirus 1 (HERV-1), may provide clues about the aberrant regulation of gene transcription that enables tumor cells to grow and survive. Understanding the Mechanism Behind […]
Earlier this summer, Promega Madison welcomed three rising researchers from Europe for an immersive experience on the company’s main campus. Alexandre Lalande (PhD student, International Center for Infectiology Research, France), Margaux Cochard (Post-Doc, University of the Littoral Opal Coast, France) and Emmanuel Heilman (Post-Doc, Medical University of Innsbruck) were selected as Young Researcher Award winners […]
Projections from the United Nations suggest that the global population reached 8 billion in 2022. By 2030, the United Nations expect the population will grow to 8.5 billion (1). In order to sustain the rapidly expanding global population, innovative approaches in the agriculture sector are required to ensure food security and safety while maintaining sustainable […]
Paraj Mandrekar began his career at Promega in 1998 in the Genetic Identity Research and Development program. In 2001, he was a consultant at the World Trade Center to help meet the urgent need to identify victims of the 9/11 attacks. Two products, one of them being our DNA IQ™ System, that Paraj and others used […]
Sickle cell disease is a debilitating blood disorder that causes recurrent pain crises and severe health effects, and can drastically impact quality of life. Recently, Vertex Pharmaceuticals and CRISPR Therapeutics introduced Casgevy, or exa-cel, a novel form of gene therapy that could radically change the management of sickle cell disease. On the heels of exa-cel’s […]
Sarah Mahan embraces change. In fact, she doesn’t just embrace it, she seeks it out, running towards change with arms wide open. “If I could do a different thing every week, I would. That’s what my job would be.” Sarah made her dream a reality when she began leading the Promega R&D Flex Team. This […]
“We are a company that is built upon innovation, and R&D is one of the main drivers of that,” says Frank Fan, Director of Biology at Promega. Promega Research and Development is focused on developing reliable tools that address the biggest problems facing life scientists. However, our R&D scientists do much more than just develop […]
