What do you wear to a job interview at a biotechnology company? How should your resume be formatted? What questions do you ask to ensure the role is a good fit?
“My mentor guided me through job applications, including helping me identify the things that were important to me in a job,” says Jazmin Santiesteban. “While we were talking about those things, she asked if I would be interested in applying to Promega.”
Jazmin received the D.O.O.R.S. Scholarship in 2021, before her senior year at Lawrence University. That scholarship program helped Jazmin develop new skills and cultivate connections that eventually led her to a job at Promega after graduation.
“I love it so far,” she says. “I don’t know where my career may take me, but right now I want to build a longer future at Promega.”
On June 15, 2023, we announced the winners of the 2023 Promega iGEM grant. Sixty-five teams submitted applications prior to the deadline with projects ranging from creating a biosensor to detect water pollution to solving limitations for CAR-T therapy in solid tumors. The teams are asking tough questions and providing thoughtful answers as they work to tackle global problems with synthetic biology solutions. Unfortunately, we could only award nine grants. Below are summaries of the problems this year’s Promega grant winners are addressing.
UCSC iGEM
The UCSC iGEM team from the University of California–Santa Cruz is seeking a solution to mitigate the harmful algal blooms caused by Microcystisaeruginosa in Pinto Lake, which is located in the center of a disadvantaged community and is a water source for crop irrigation. By engineering an organism to produce microcystin degrading enzymes found in certain Sphingopyxis bacteria, the goal is to reduce microcystin toxin levels in the water. The project involves isolating the genes of interest, testing their efficacy in E. coli, evaluating enzyme production and product degradation, and ultimately transforming all three genes into a single organism. The approach of in-situ enzyme production offers a potential solution without introducing modified organisms into the environment, as the enzymes naturally degrade over time.
IISc-Bengaluru
Endometriosis is a condition that affects roughly 190 million (10%) women of reproductive age worldwide. Currently, there is no treatment for endometriosis except surgery and hormonal therapy, and both approaches have limitations. The IISc-Bengaluru team at the Indian Institute of Science, Bengaluru, India, received 2023 Promega iGEM grant support to investigate the inflammatory nature of endometriosis by targeting IL-8 (interleukin-8) a cytokine. Research by other groups has snow that targeting IL-8 can reduce endometriotic tissue. This team will be attempting to create an mRNA vaccine to introduce mRNA for antibody against IL-8 into affected tissue. The team is devising a new delivery mechanism using aptides to maximize the delivery of the vaccine to the affected tissues.
When six undergraduate students from across the country convened at Promega Madison to present their research, several of them were surprised to see Promega CEO Bill Linton in the audience.”
“I’ve never interacted with a biotechnology company like this, and then the CEO shows up,” says Valeria Sanchez Estrada. “We actually discussed ChatGPT and how AI and machine learning can advance biology research.”
Valeria, a second-year student from St. John’s University, was a 2022 recipient of the Diversification Of Our Research Scientists (D.O.O.R.S.) Scholarship, provided the BioPharmaceutical Technology Center Institute and Promega North America. The scholarship provides ten students with a $5,000 award that can be used towards educational fees, books and supplies to support their scientific education. The scholarship is open to undergraduate students from underrepresented backgrounds pursuing a biotechnology-related major.
On March 24, 2023, scholarship recipients were invited to Promega Madison for the first in-person D.O.O.R.S. Scholars Day. In addition to presenting their research, students had the opportunity to meet with Promega R&D scientists and tour the beautiful Kornberg Center. Overall, the event was a day of celebration and building connections between outstanding students and the biotechnology industry.
“I imagined industry just being about hard science and lab time,” says Chris Provido, a third-year student from Bowie State University. “But Promega’s values showed me today that although we’re all scientists, your humanity is just as important, and it’s important to find a balance between hard science and being human.”
The Biotechnology Youth Apprenticeship Program hosted by the BTC Institute gives high school students an opportunity to gain hands-on experience in a research lab. Students can work as paid apprentices for either one or two years while also attending weekly training sessions at the BioPharmaceutical Technology Center. Through this program, students can graduate high school with robust knowledge of lab safety and fundamental techniques, as well as a strong understanding of the soft skills required to succeed in science, from reading peer-reviewed literature to delivering a research presentation.
Many of these students will grow up to pursue careers in science, from academic research labs to the biotechnology industry. Some of them have returned to Fitchburg to work at Promega, the primary corporate sponsor of BTC Institute. As these scientists progress in their careers, the skills they developed in the Youth Apprenticeship Program continue to support their work every day.
On a hill at the top of the Promega Madison campus, an old observatory overlooks the city of Fitchburg, Wisconsin. Inside, cutting-edge telescopes are ready to give students and astronomers breathtaking views of the cosmos.
Over the past 140 years, this observatory has served as the first launchpad for storied careers in astronomy. Following a relocation, it gave a passionate community a home for their curiosity. Today, it supports modern research while also welcoming stargazers of all ages. It is now one of the oldest operational observatories in the United States. This is the Bell Burnell Observatory.
World Youth Skills Day provides a unique opportunity to emphasize the importance of equipping young people with experiences, skills, and opportunities in the workforce. This celebratory day falls on July 15th and was officially declared by the United Nations General Assembly in 2014.
At Promega, we are constantly adhering to invest in the future generations of science—and the BioPharmaceutical Technology Center Institute (BTC Institute) serves this mission best. The BTC Institute is a non-profit organization that provides educational, scientific, and cultural opportunities for people of all ages. Each summer, the organization hosts a wide range of experiences including camps, programs, and field trips to support individuals interested in science. In the spirit of World Youth Skills Day, let’s take a look at some experiences that are offered for young learners in summer 2022.
In late May 2022, Promega invited the nine finalists for the Promega Brazil Young Researcher Award to present their work at a Student Research Symposium on the Promega Madison campus.
The Brazil Young Researcher Award program was created to acknowledge exceptional work by Brazilian students utilizing Promega products in their research. These student researchers were recognized for their achievements and were given the opportunity to present their innovative research to Promega scientists as part of a week-long immersive experience on the Promega campus.
“I want to make sure that what I think I want to do, truly is what I want to do.”
Anusha Ray Dey started working in a research lab as an undergraduate at the University of Wisconsin-Madison because she imagined it would improve her future application to medical school. However, there was one twist she didn’t see coming – Anusha realized she really enjoyed working in research. Now graduated, she’s earning a Masters degree to gain more experience before making her next decision.
“I could go into industry and do research, or even be a research coordinator. But maybe I’ll decide to still go on to medical school,” Anusha says. “My experiences in research definitely did shift my plans.”
Supporting Mental Health on Campus
Anusha Ray Dey completed an undergraduate thesis searching for chemical signals in the urine of male orangutans. She has a black belt in tae kwon do and she loves to draw. For an honors project, she drew all of the illustrations for an animated video on Alzheimer’s Disease.
Welcome back to the third and final part of our Women in Science series, where we’ve been exploring the key factors that perpetuate the gender gap in STEM. In Part 1 of this series, Breaking the Bias: Addressing the STEM Gender Gap, we dug into the key factors of gender stereotypes and male-dominated culture. Part 2, This is What a Scientist Looks Like: The Importance of Female Role Models in STEM, was all about the issue of fewer visible female role models in STEM. Last but certainly not least, this installment will focus on tackling the issue of the confidence gap, including the factors that play into it and the myriad ways we see it unfolds.
Part of my exploration of this topic included having conversations with a handful of my incredible female colleagues at Promega about the challenges women in STEM face. These colleagues were (in no particular order): Becky Godat, Instrumentation Scientist; Jacqui Mendez-Johnson, Quality Assurance Scientist; Johanna Lee, Content Lead, Marketing Services; Jen Romanin, Sr. Director, IVD Operations and Global Support Services; Kris Pearson, Director, Manufacturing & Custom Operations; Leta Steffen, Supervisor, Scientific Applications; Monica Yue, Technical Services Scientist; and Poonam Gunjal, Manager, Regional Sales.
Welcome back to Part 2 of our March Women in Science series! In Part 1 of this series, Breaking the Bias: Addressing the STEM Gender Gap, we took a closer look at gender stereotypes and male-dominated culture and their roles as key factors in perpetuating the gender gap in STEM. In this installment, we will be continuing the conversation about the STEM gender gap and focusing on the key issue of fewer female role models in STEM.
Part of my exploration of this topic included having conversations with a handful of my female colleagues at Promega about the about the challenges women in STEM face. These colleagues were (in no particular order): Monica Yue, Technical Services Scientist; Poonam Gunjal, Manager, Regional Sales; Becky Godat, Instrumentation Scientist; Leta Steffen, Supervisor, Scientific Applications; Kris Pearson, Director, Manufacturing & Custom Operations; Jacqui Mendez-Johnson, Quality Assurance Scientist; Johanna Lee, Content Lead, Marketing Services; and Jen Romanin, Sr. Director, IVD Operations and Global Support Services.
What Does A Scientist Look Like?
If someone asked you to draw a scientist, what would that person look like? Over the past 5 decades, this question has been asked of over 20,000 students across all grades from kindergarten through 12th, and evaluated in nearly 80 studies. A meta-analysis of these decades of studies revealed some interesting findings.
Between 1966 and 1977, of the 5,000 drawings collected from students during the original 11-year study, only 28 of those 5,000 drawings (less than 1% of the drawings) depicted a female scientist, with all 28 of them being drawn by girls.
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