iGEM: Saving the World with Science

The University of Chicago 2016 iGEM team group photo (Photo credit: Julia Byeon)

Every year, groups of teenagers gather together and brainstorm ways to save the world—with science. The International Genetically Engineered Machine (iGEM) Foundation is a non-profit organization that is dedicated to educating young scientists and enhancing open community and collaboration in the field of synthetic biology. They hold a competition every year with hundreds of teams participating from around the world.

Last year, Promega provided cloning reagents to the University of Chicago iGEM team, and they received a bronze medal for their work. We asked two of the team members, Steve Dvorkin and Julia Byeon, about their experience. Steve is a junior and majors in biology; he is co-president of the team this year. Julia recently graduated and works in public policy. Continue reading “iGEM: Saving the World with Science”

“Reverse” Molecular Reactions in DNA through Mind-Body Interventions

While my morning routine typically only involves a large cup of coffee, increasingly more Americans are beginning their days with a set of sun salutations. Sun salutations are a series of poses originating from yoga, one of the most popular types of mind-body interventions in the United States. Along with yoga, other commonly recognized mind-body interventions (MBI) include meditation, mindfulness, Tai chi, and Qigong. Despite the fact that each of these activities differ in the amount of physical effort required, they all view mental and physical health as single cohesive system.

The influence of overall mind-body intervention on health and wellness is an ancient concept that is now revolutionizing Western medicine. In the past, Western medicine has focused primarily on the health of the physical body. Yoga and meditation were viewed as beneficial, but were less likely to be recommended by clinicians as a method for relief. Now, with recent developments in gene expression analysis techniques, we have a better understanding of biological mechanisms and how they interact with psychological variables. A possible shift in clinician’s philosophies can be seen in the steady rise in the complementary health approaches of yoga, Tai chi, and qi gong1.

To completely understand how MBI affects a person’s health, we must first realize the links between stress and the conserved transcriptional response to adversity (CTRA). CTRA refers to the common molecular pattern discovered in individuals facing hardship. Whether it be in the form of diagnosis of a life-threatening disease or the death of a loved one, the characteristics of CTRA stay consistent. CTRA causes an influx in the production of epinephrine and norepinephrine. These neuromodulators then affect the production of transcription factors.

Continue reading ““Reverse” Molecular Reactions in DNA through Mind-Body Interventions”

Helping Others through Science and Service

Science has been an important part of my life for a long time. One of my motivations for being a scientist was helping others. As scientists, there are many ways that we make a difference. For example, doing research that reveals information about basic biological processes can provide insight into how a disease might wreak havoc, and in turn facilitate drug design and effective disease treatments. I can say from experience that it’s especially rewarding to go beyond the impact of science to assist someone in the community face to face.

A St. Vincent de Paul Food Pantry host helps a client to shop for food.

Just over 5 years ago, I started volunteering at the St. Vincent de Paul Madison Food Pantry, the largest in Dane County, Wisconsin, which serves an average of about 400 families per week1. The pantry uses a customer-choice model in which clients are allotted points to shop for food, allowing them to make selections that preserve their dignity and ethnic diversity. The food pantry has a small staff, so volunteers are vital to keep things running. I serve as a “host” to clients and assist them to shop around the pantry for the items that they need. It has been such a positive experience for me. In the grand scheme of things, I’m not changing the world, but I’m helping others get essential items to make ends meet for their family. Tough times can happen to anyone, and it takes a great deal of courage to ask for help. My goal is to make the experience for clients as positive as possible by being cheerful, courteous and respectful during their time at the pantry. If helping others can make one individual forget even for a moment that they have fallen on hard times, then I call that a win!

A desire to make a difference in the community through volunteerism is one of the characteristics that I really like about working at Promega. At a recent company meeting, employees were asked to share how they serve the community. Activities ranged from assisting those with disabilities to participate in athletic activities to taking care of shelter animals to starting a non-profit for children in need. There were many more! Employees are helping others in their local communities and even those across the globe from where they live. It was so inspiring to hear about my colleagues’ experiences of serving others.

Promega has a mechanism for employees to apply for time off to volunteer through the Promega in Action program.

Continue reading “Helping Others through Science and Service”

A Successful Launch for Biotechnology: The Basics for Middle School Teachers

Megan Wagner (left) and Katie Aliota, science teachers from Cardinal Heights Upper Middle School in Sun Prairie, WI; load an agarose gel with colored dyes.
Megan Wagner (left) and Katie Aliota, science teachers from Cardinal Heights Upper Middle School in Sun Prairie, WI; load an agarose gel with colored dyes.

Today’s blog is jointly written by guest blogger  Peter Kritsch, Biotechnology and Biology Teacher at Oregon High School and contributor Barbara Bielec. K-12 Program Director at the BTC Institute.

The BTC Institute has offered two graduate-level courses for high school teachers for many summers.  Biotechnology: The Basics and Biotechnology: Beyond the Basics have become very popular and are also drawing the interest of middle school teachers.  So, this June we piloted a new 3-day course designed specifically for them.  Representing different schools and districts, eight teachers learned how to extract DNA from strawberries, pour and run agarose gels, identify a taste gene, and received information on lots of resources to use with their students.

Through the BTC Institute’s Biotechnology Teacher Academy, these courses are offered at no cost and $300-$500 stipends are available.  A main Academy goal is to provide high quality professional development opportunities that prioritize content that participants can smoothly incorporate into their classrooms.   Our commitment to stipends is generously supported by the Wisconsin Space Grant Consortium (WSGC), Promega Corporation, Madison College and the BTC Institute.  (All three courses are offered for graduate credits from Edgewood College, and Viterbo University also offers credits for the two geared to high school teachers.)

The importance of this approach is affirmed by Sherry Jacobsen (Kromrey Middle School in Middleton, WI):

This [course] is such a gift to teachers!  Many times we aren’t treated as professionals so it was nice to be treated as a professional without a high personal cost.  I love how the course is so practical.  Many courses are only in theory and no application.  I can take so many useful ideas with me.

Biotechnology is making its way into the middle school classroom. With access to the BTC Institute’s Equipment Loan Program, teachers can check out micropipettes, gel boxes & power supplies, an ultraviolet light box and other equipment for up to two weeks.  Course participant Amy Reimer (Core Knowledge Middle School in Verona, WI), has already taken advantage of this program and noted that it was “great to review procedures” through the course and plans to borrow equipment again this coming year. Continue reading “A Successful Launch for Biotechnology: The Basics for Middle School Teachers”

Biotechnology Youth Apprentice Madhu Gowda Wins GRAND PRIZE at the Capital Science and Engineering Fair

Madhu presents her work.
Madhu presents her work.

Imagine the pleasure Barbara Bielec, the BTC Institute’s K-12 Program Director and co-coordinator of the Dane County Youth Apprenticeship Program in Biotechnology (YAP-Biotechnology), felt when reading this recent message from Sharon Tang, one of our apprentice’s mentors:

“I am unbelievably proud to let you know that Madhu won not only first place for the biological science projects, but also the GRAND PRIZE at the Capital Science and Engineering Fair this weekend! She was at the fair from 7:30am until 4:30pm presenting her work done in our lab and did a fantastic, eloquent job speaking about her project. This was such an impressive honor – she won among over 20 competing students in the region, earned a cash award, and will be competing as a finalist at the Intel international science fair in May. I’m sure she’ll tell you, but I am just over the moon and wanted to share the news as well. Attaching a photo I took of her in action.”

A second year student in the program, Madhu is a senior at Middleton High School. Since November, 2015, she has been working in the lab of Dr. Susan Thibeault in the Department of Surgery, Division of Otolaryngology – Head & Neck Surgery at the University of Wisconsin-Madison.

Continue reading “Biotechnology Youth Apprentice Madhu Gowda Wins GRAND PRIZE at the Capital Science and Engineering Fair”

Summer 2016: Exciting Science Programs for Kids at the BTC Institute!

First, a quick update: Hard to believe, but we’re in our 21st academic year at the BioPharmaceutical Technology Center Institute (BTC Institute).  February finds us immersed in our usual second semester offerings.  Our Biotechnology Field Trips program is on the way to record attendance, but it’s not too late for you to schedule a visit for this spring, or for a group this summer: btci blog photo 2http://www.btci.org/k12/bft/bft.html.

We’re also pleased to report that work site mentors have been found for almost all of the juniors and seniors enrolled in the State of Wisconsin Youth Apprenticeship Program in Biotechnology – Dane County (http://www.btci.org/k12/yap/yap.html).

Now, let’s turn our attention to Summer 2016.  We’re excited to once again offer great opportunities for upper elementary, middle and high school students to engage in activities that will allow them to explore their interests in the life sciences – and to learn a lot along the way. And, it’s not too soon to think about summer! Here’s a rundown of what’s in store: Continue reading “Summer 2016: Exciting Science Programs for Kids at the BTC Institute!”

Building Community: Outreach through BTC Institute Courses and Activities

Students in the Core Techniques in Protein and  Genetic Engineering Course (photo credit BTCI)
Students in the Core Techniques in Protein and Genetic Engineering Course (photo credit BTCI)

One of the questions that Promega has always asked of itself is “How can a company really become a vital part of its community over the long term, making truly valuable and unique contributions that foster deep connections to local communities where it exists?”  Lately we have formalized that with our Corporate Responsibility Report, but this question has always been a part of our corporate culture, long before such thinking was popular or “en vogue”.

In 1993 Promega helped to begin the nonprofit educational outreach institution, the BTC institute, this long-term commitment to the local community has grown throughout the 22 years to become an integral part of the local Wisconsin educational community and serve as a model for global partners as well. Here are a few thoughts from the Karin Borgh, the Executive Director of BTC Institute, about how it has managed to work toward a vision of being a vital, contributing member of the community. Continue reading “Building Community: Outreach through BTC Institute Courses and Activities”

A Celebration of Life XX—Wild Weather!

Summer Science Vacation
Summer Science Vacation

The African American Ethnic Academy and the BioPharmaceutical Technology Center Institute (BTC Institute), both 501(c)(3) non-profit educational organizations, have collaborated for twenty years in offering A Celebration of Life, a summer science program for upper elementary and middle school students. The program is open to all area students, with tuition reimbursement and transportation provided for those who need that assistance.

With supporting grants from the Wisconsin Space Grant Consortium, an educational arm of NASA, two summer science camps are offered this year – one for upper elementary and one for middle schools students. We just completed the first session, full mornings for two weeks for students entering 3rd–5th grade and have launched the second one, same format, for middle school students this week.

Needless to say, the theme of Wild Weather! lends itself to a wide array of hands-on, exploratory activities.  Here are a few of our favorites that you may wish to try out with the kids in your life. Continue reading “A Celebration of Life XX—Wild Weather!”