Strengthening Water Safety Measures with Advanced Detection

Detecting Legionella in water systems is a critical step in preventing outbreaks of Legionnaires’ disease. However, not all detection methods are created equal. One of the biggest challenges in water testing is differentiating between viable and non-viable cells. This distinction is essential for making informed decisions about water system safety and compliance, especially in high-stakes environments like hospitals, office buildings and public spaces.

In a previous blog, we explored the history and significance of Legionella testing, from its discovery during the 1976 outbreak to the risks posed by modern water systems. We also highlighted the limitations of traditional culture-based detection and the need for advanced tools to improve accuracy and speed. In this second blog, we will dive deeper into the challenges of Legionella detection, the science behind qPCR technology and how an innovative approach to qPCR addresses these challenges. Finally, we will demonstrate how this technology fits into established workflows to deliver reliable, actionable results for water safety. 

Common water testing icons are shown with blue circles, including a water faucet, water testing imagery, water droplets, water droplets with a magnifying glass, and a water droplet on a clipboard.
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Figure Methodology: The Balance Between Accuracy and Aesthetics

Concept image of the balance between scientific accuracy and aesthetics.
Generated with DALL-E.

In the ever-changing landscape of life sciences, the relationship between science and design remains essential. For example, have you ever read a blog or article overloaded with excessive terminology? Or an advertisement with complex information or graphics? This can be overwhelming and may cause you to miss the key message. Similarly, when an image is overly designed, it risks missing the mark entirely.

Enter the scientific figures. Whether the data is conveyed through complex graphs or scientific illustrations, design plays a vital role in providing clarity to the story. With that in mind, here are a few tips I’ve learned as a designer working with scientists in the life science and healthcare fields that can help you collaborate more effectively:

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Understanding Stress Resilience in Tomatoes: Insights Into the Role of PP2C Genes

An illustration of a tomato plant divided between normal and drought conditions. This study looks at the role of PP2C in stress response.

As climate change accelerates, understanding how crops survive environmental stress isn’t just an academic question—it’s a critical challenge for global food security. Tomatoes (Solanum lycopersicum), a staple crop worldwide, face increasing threats from drought, salinity, and extreme temperatures. But how do these plants adapt at the molecular level?

A recent study published in Scientific Reports ​investigated the evolutionary history, genomic diversity, and functional roles of protein phosphatase 2C (PP2C) genes in tomatoes (1). Instead of merely cataloging these genes, the researchers analyzed how PP2C gene expression changes under environmental stress. This information could help inform us about crop improvement strategies.

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Celebrating Creativity and Innovation: The 2025 Promega Employee Art Showcase

At Promega, we believe that creativity drives innovation, challenges conventional thinking, and amplifies our ability to solve complex problems. Our annual Employee Art Showcase, a tradition since 1998, serves as a perfect expression of this belief. This event highlights the incredible creative talents of our employees and their families, offering a space to explore art in all its forms.

This year’s event was nothing short of inspiring, with 130 pieces of art submitted by employees and their families, beautifully displayed at the BioPharmaceutical Technology Center on the Promega Madison campus. The opening reception, held on January 16, featured a lively atmosphere with music performed by the Promega band, Major Groove, and a cozy hot cocoa bar—setting the perfect stage for appreciating the diverse artwork on display.

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From PhD to Communications in Four Phases: A Practical Guide to Uncover your Career Skills

Remember learning to swim and realizing you could float without trying? While floating alone did not make you fit for the Olympics, it did mean you were ready to start learning the moves without sinking. As a PhD student or recent graduate exploring a career away from research, you might feel similarly unprepared, but without realizing it, you have been building the skills you need right from the start.

Phase 1: Exploration

In every PhD comes a time where you must decide between following the academic route, switching to research in industry, or leaving the bench behind altogether. Facing this decision, you might find yourself facing more questions than answers or even start to doubt your choice of degree. If this is the case, let me reassure you, you are not alone.

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Bacteria From Insect Guts Could Help Degrade Plastic

For the past few decades, plastic pollution has become a serious environmental challenge. Plastic production has continued to increase and there are a variety of plastic polymer types available. Polystyrene (PS) is one of the most widely used plastics due to its durability, strength, and low cost. However, the qualities that make this plastic valuable also make it highly resistant to degradation.

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Glo-ing Above and Beyond: Simplifying Science with MyGlo Reagent Reader

Introduction

When it comes to laboratory tools, few things resonate more than the experiences of researchers who rely on them daily. At the University of Cincinnati the MyGlo Reagent Reader has quickly become an indispensable lab companion, due to its compact design, affordability, and intuitive interface with tailored apps for Promega assays. But what truly sets the MyGlo Reagent Reader apart is how it empowers scientists to focus on their research.

Take Ipsita Kundu, a third-year PhD student at the University of Cincinnati working in Dr. Tim Phoenix’s lab. The Phoenix lab, dedicated to studying innovative brain tumor therapies, faced challenges with their outdated luminescence reader. They needed an affordable, reliable solution to streamline Ipsita’s experiments without compromising accuracy or efficiency.

The MyGlo Reagent Reader was the answer. This blog highlights how this integrated solution is redefining laboratory workflows, enabling researchers to maximize productivity and maintain focus on groundbreaking discoveries. Let’s delve into Ipsita’s story and explore how MyGlo transformed her research.

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Exploring Career Options for PhD Students: Planning for Success

Earning a PhD opens doors to a wide range of career opportunities across academia, industry, government, and beyond. While many students begin their PhD programs with specific career goals, research shows that career interests often evolve during their training (Brown et al., 2023). Therefore, exploring career options and remaining flexible to opportunities is important. By embracing career exploration and self-assessment, students can identify their best career options and make informed decisions about their next steps after graduation.

The Many Career Options for PhD Graduates

PhD graduates today find themselves in diverse roles, with opportunities extending beyond traditional academia. Career paths include:

  • Academia: Research-intensive faculty positions, teaching-focused roles, or administrative leadership.
  • Industry: Roles in biotechnology, data science, or consulting, often in research or management positions.
  • Government and Nonprofit Organizations: Research or policy roles in agencies such as the NIH (National Institutes of Health) and FDA (Food and Drug Administration), and others.
  • Additional Careers: Science communication, medical writing, marketing, patent law, or entrepreneurship.

During their training, PhD students develop highly transferable skills—critical thinking, project management, data analysis, communication, and problem-solving—that are highly valued across sectors (Sinche et al., 2017). Recognizing the value of these skills can expand career options for graduates.

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Understanding and Combating Legionella in Water Systems with Viability PCR

Water plays a vital role in countless aspects of daily life—drinking, cooling, recreation and more. However, the same systems that deliver these benefits can also harbor Legionella, a waterborne bacteria responsible for Legionnaires’ disease, a severe form of pneumonia (1). Legionella thrives in stagnant aquatic environments, many of which are human-made and common in modern infrastructure, like in cooling towers, hot tubs and complex building water systems. In this blog, we explore the risks posed by Legionella, the limitations of traditional detection methods and how advanced tools at Promega are transforming water safety monitoring. 

3D illustration showing legionella pneumophilia bacteria in water
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Do Zebrafish Hold the Key to Heart Regeneration? 

Heart regeneration after heart attacks can stop poor health outcomes, read for more research

The human body has an incredible capacity for self-repair. Our skin can regenerate after a small cut, bones can heal after fractures and even the liver can regrow to its original size after 70% is lost or removed (3). However, when it comes to the heart, the story is very different. As Miley Cyrus once sang, “nothing breaks like a heart” – and science agrees. Unlike other organs, the heart has almost no ability to regenerate itself after injuries. In instances like myocardial infarctions, more commonly known as heart attacks, large amounts of cardiomyocytes (CMs)—the cells responsible for heart muscle contraction—are lost and cannot be regenerated, causing the formation of non-regenerative fibrotic scar tissue and, ultimately, decline in heart function (1).  

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